منابع مشابه
Universal influenza vaccination: the time to act is now.
Annual influenza epidemics create a significant public health burden each year in the United States. That influenza continues to pose a public health threat despite being largely preventable through vaccination is indicative of continuing weaknesses in the U.S.'s public health system. Moreover, the burden of annual influenza epidemics and the fragility and instability of the capacity to respond...
متن کاملSmallpox Vaccination
This article was presented by the author at the Vaccination Seminar of May 26, 1972, National University Medical School.
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BACKGROUND Ten to 30% of HIV-1 infected subjects develop broadly neutralizing antibodies (bNAbs) during chronic infection. We hypothesized that immunizing rabbits with viral envelope glycoproteins (Envs) from these patients may induce bNAbs, when formulated as a trimeric protein and in the presence of an adjuvant. METHODS Based on in vitro neutralizing activity in serum, patients with bNAbs w...
متن کاملThe Political Consequences of Franchise Extension: Evidence from the Second Reform Act
We use evidence from the Second Reform Act, introduced in the United Kingdom in 1867, to analyze the impact on electoral outcomes of extending the vote to the unskilled urban population. Exploiting the sharp change in the electorate caused by franchise extension, we separate the effect of reform from that of underlying constituency level traits correlated with the voting population. Although we...
متن کاملExtension of Lifespan in C. elegans by Naphthoquinones That Act through Stress Hormesis Mechanisms
Hormesis occurs when a low level stress elicits adaptive beneficial responses that protect against subsequent exposure to severe stress. Recent findings suggest that mild oxidative and thermal stress can extend lifespan by hormetic mechanisms. Here we show that the botanical pesticide plumbagin, while toxic to C. elegans nematodes at high doses, extends lifespan at low doses. Because plumbagin ...
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ژورنال
عنوان ژورنال: The Lancet
سال: 1853
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(02)53114-7